January 2019

Partnering to Improve Outcomes

We’re off to a great start in 2019 and have already delivered lung cancer education through our Speaker’s Bureau to more than 490 people, 80 patient resource goody bags to our partner hospitals, and several patients to treatment through our driving program. Joe, lung cancer patient and recent ride recipient, had this to say, “My driver was very friendly. This was our first ride – I’m hoping we can get him the next time we call in!”

A Breath of Hope was honored at the Mille Lacs Tribe Pow-Wow in Northern Minnesota Saturday for donating screening grants that helped build a lung cancer screening program on the reservation. More than 300 Native Americans from all generations attended the pow-wow, many dressed in full regalia. Director Nancy Torrison and board member, Dr. Abbie Begnaud were present to meet with medical leaders from the community and participate in the event.

A Breath of Hope has begun work with the MN Dept. of Health to develop a radon mitigation program for low income communities. Radon is the second leading cause of lung cancer and is found in 2 of 5 MN homes. While kits are only $10, mitigation can run $1500 to $2000. Our goal is to educate all communities about this risk, and help mitigate homes for whom the cost is prohibitive.

ABOH will present at the Cancer Summit Minnesota February 28th. Click here for more information or to register.

#StrongerTogether #CollaboratingToSaveLives

 

Research for Improved Treatments

A Progress Report from 2017 ABOH Research Award winners, Drs. Stabile and Burns:

We are pleased to report progress by our multidisciplinary research team in understanding how the female sex hormone, estrogen, promotes a pro-tumor immunosuppressive lung tumor microenvironment that allows the tumor to evade the immune system and whether we can improve the activity of immunotherapy using anti-estrogens. Since our project was funded, there has been even further rationale for our studies including published reports that female lung cancer patients who receive immunotherapy do not benefit from this therapy as much as male lung cancer patients. This sex-dependent difference in reduced immunotherapy efficacy highlight the importance of further interrogation of the mechanistic basis for these observations, especially since female lung cancer patients generally have better survival than male patients.

We have made significant progress in the first 6 months of funding. First, we have modified our preclinical approach to use a more physiologically relevant mouse model that allows us to grow our novel tobacco carcinogen-induced lung tumor cells directly in the lung. Second, we have generated new data showing that dual therapy with the anti-estrogen fulvestrant and an anti-PD-L1 agent can decrease the ability of lung cancer cells to metastasize and grow in the lungs. Continue reading…

 

Events that Build Community & Momentum

The 7th Annual ABOH Women’s Wellness Tea is Saturday, March 16th at the Wayzata Country Club. Registration is now open! Join hundreds of women to focus on women’s health issues, well-being, and becoming your best self.

Event Itinerary:

10:00 a.m. Doors open
10:00 – 11:00 a.m. Bags, Bling, and Beauty Silent Auction, Mimosa & Bloody Mary Bar, Wine Wall and Raffle
11:00 – 12:15 p.m. Brunch and program. Oprah recently referred to our keynote speaker, Sarah Rudell Beach, as a “mindfulness guru”. Sarah will be speaking on the topic of stress reduction, well-being and mindfulness
12:30 – 1:30 p.m. Break out sessions:

  • Nutrition: Eat Right to Sleep Tight
  • Journaling: Planning for Self-care
  • Mindfulness: Stress Less

1:30 p.m. Auction checkout, mingling and private breakout session for lung cancer survivors. Survivors are invited to retreat to the second floor board room at the country club at 1:30. This one hour facilitated meeting will also serve as the March Women & Lung Cancer Support Group meeting.